About 164 million American adults struggle to get to sleep at least as soon as a week, according to a 2016 survey from Customer Reports, and practically a single third have turned to drugs like Ambien or supplements like melatonin to discover relief. Increasingly, persons are also questioning if CBD could be the essential to much better sleep — but some analysis suggests a diverse cannabis compound may have extra to supply in this division: CBN. And unsurprisingly, brands are prepared to capitalize on its snooze-inducing powers.
A single of the initial to pounce is CaniBrands, whose new Can-i-Sleep vape pen is the initial of its sort to function a CBN-dominant oil blend. Containing 500 mg of cannabis oil with a 12 % CBN content material, it is becoming marketed especially to insomniacs and other persons dealing with sleep concerns. As the company’s CEO told Yahoo Finance, “Our business is advocating for cannabinoid therapy to be the initial option, not the option, to resolving widespread ailments like sleeplessness and insomnia,” and vape pens — whose effects are practically instantaneous — are a logical spot to get started.
Even though analysis on CBN and sleep is nevertheless preliminary, a 1995 study published in the Chemical & Pharmaceutical Bulletin indicated that the cannabinoid not only improves the excellent of sleep but may well also prolong its length (although this ought to be taken with a grain of salt, as the study was performed on mice rather than humans).
Researchers think it does so by activating a response in the CB2 receptors, which are a single of two major receptors in the body’s endocannabinoid program. Although CB1 receptors (discovered mostly in the brain) enable regulate power, mood, and appetite, CB2 receptors (which are discovered all through the immune program, skeletal program, and peripheral nervous program) have a stronger impact on discomfort. According to Dr. Jacyln Tolentino, a practitioner of clinical cannabinoid medicine, this “may account for [CBN’s] reported advantage as a sleep help,” as she told Bustle.
The Age of Specialized Cannabis Vape Pens Is Upon Us
As cannabis buyers turn into extra sophisticated and discerning, they’re also looking for out extra specialized options for the circumstances they’re attempting to treat. Currently, not only is there a cannabis chocolate for each and every mood, but metered cannabis dose pens for distinct purposes are also becoming extra prevalent — and the quest for much better sleep is a single of the most significant motives persons are deciding on them.
Some of these items include CBN (for instance, the “Rest” vape pen from Sunday Goods proudly advertises its 10:five:1 ratio of THC to CBD to CBN) although none pack the potency of the new Can-i-Sleep pen. This is maybe unsurprising — CBN is only present in trace amounts in most cannabis strains, due to the fact it is only formed when THC degrades, and extracting it in considerable quantities presents a technical challenge.
Having said that, the cannabis business has established itself to be adept at overcoming such challenges (if growers can develop a THC-totally free version of hemp, they can figure out how to develop strains with extra CBN). Going forward, as persons turn into extra familiar with the prospective added benefits of previously-obscure cannabinoids, it is most likely that other cannabis compounds will quickly be starring in their personal speciality vape pens — and in truth, this course of action has currently began.
A prime instance is the compound THCV, which has shown early proof of becoming an powerful appetite suppressor. Because persons looking for to consume significantly less have quite a few of the similar specifications in a item as persons looking for to sleep extra (i.e. it ought to be quick to use and deliver quickly-acting relief), THCV vape pens make sense for the similar motives CBN pens do. Brands like California Cannabinoids have currently released such items (their Doug’s Varin vape pen has involving 25-30 % THCV) and this trend is most likely to only accelerate in the future.