Cannabis has been legalized in some type for a great deal of the United States. The National Institute for Occupational Security and Wellness (NIOSH) received a well being hazard evaluation request from a Minnesota cannabis facility and their union to undertake an evaluation.


NIOSH representatives visited the facility in August 2016 and April 2017. Surface wipe samples had been collected for evaluation of delta-9 tetrahydrocannabinol (Δ9-THC), delta-9 tetrahydrocannabinol acid (Δ9-THCA), cannabidiol, and cannabinol. Environmental air samples had been collected for volatile organic compounds (VOCs), endotoxins (limulus amebocyte lysate assay), and fungal diversity (NIOSH two-stage BC251 bioaerosol sampler with internal transcribed spacer area sequencing evaluation).

Final results:

Surface wipe samples identified Δ9-THC all through the facility. Diacetyl and two,three-pentanedione had been measured in initial VOC screening and subsequent sampling for the duration of tasks exactly where heat transference was greatest, even though levels had been effectively beneath the NIOSH advisable exposure limits. Endotoxin concentrations had been highest for the duration of processing activities, even though internal transcribed spacer area sequencing revealed that the Basidiomycota genus, Wallemia, had the highest relative abundance.


To the authors’ information, this is the initially published report of prospective diacetyl and two,three-pentanedione exposure in the cannabis market, most notably for the duration of cannabis decarboxylation. Endotoxin exposure was elevated for the duration of grinding, indicating that this is a potentially higher-danger job. The findings indicate that prospective well being hazards of significance are present for the duration of cannabis processing, and employers ought to be conscious of prospective exposures to VOCs, endotoxin, and fungi. Additional study into the degree of respiratory and dermal hazards and resulting well being effects in this market is advisable.