Cannabinoid-primarily based drugs as anti-inflammatory therapeutics


In the nineteenth century,  marijuana was prescribed by physicians for maladies ranging from consuming problems to rabies. On the other hand, as newer, far more productive drugs have been found and as the prospective for abuse of  marijuana was recognized, its use as a therapeutic became restricted, and only lately has its therapeutic prospective been re-evaluated. Current research in animal models and in humans have developed promising final results for the remedy of numerous problems – such as obesity, cancer, and spasticity and tremor due to neuropathology – with drugs primarily based on  marijuana-derived cannabinoids. Additionally, as I go over right here, a wealth of data also indicates that these drugs have immunosuppressive and anti-inflammatory properties thus, on the basis of this mode of action, the therapeutic usefulness of these drugs in chronic inflammatory illnesses is now becoming reassessed.

Copyright © 2018 Elsevier B.V. All rights reserved.
PMID: 15864274 DOI: 10.1038/nri1602





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