Researchers, out of the Emory University College of Medicine, publishing a study in Neuropsychopharmacology, have discovered that escalating or decreasing the body’s endocannabinoid levels has important impacts on eliminating worry-related memories. Endocannabinoids are the body’s naturally-made cannabinoids and have been strongly linked to regulating the body’s worry responses.

In this study, it was demonstrated in mice models that disrupting the endocannabinoid program by blocking cannabinoid receptors enhanced the retention of memories related with worry. On the other hand, it was shown that escalating the body’s endocannabinoid levels by stopping their breakdown decreased the retention of worry-related memories. On top of that, mice with enhanced endocannabinoid levels have been much less probably to have worry-responses return when researchers attempted to reinstate them.

These benefits have profound implications for the remedy and even the prevention of Post-Traumatic Anxiety Disorder, or PTSD. The disorder is usually treated with anti-depressants, but these drugs treat the symptoms of PTSD rather than its causes. If this study’s benefits hold accurate, the body’s endocannabinoid program could be the 1st line of defense against building PTSD. CBD is believed to possibly raise the naturally-made endocannabinoid levels[1], suggesting it could play a crucial part in treating and stopping PTSD by lowering the retention of worry-related memories.

The article’s abstract can be discovered right here.


[1] Ujváry I, Hanus L (2014). “Human metabolites of cannabidiol: a overview on their formation, biological activity, and relevance in therapy”. Cannabis and Cannabinoid Study. 1 (1): 90–101.