Neuroprotective effects of endocannabinoids following traumatic brain injury


A group of researchers out of Israel have published a study that suggests the body’s endocannabinoids may possibly play a protective function in the brain right after sustaining serious head injury. These endocannabinoids basically lead to enhanced recovery from brain injury by defending the brain from itself.

Researchers utilised a naturally occurring brain compound related to the body’s cannabinoids to study the impact of cannabinoids in treating head injury in mice models. When serious head injury happens, the brain is broken not only from the trauma of the initial injury but also in aspect by accidentally harming itself although it attempts to repair. In the study, the cannabinoid-like compound was largely profitable in stopping the brain from damaging itself in the repair phase of head trauma. In addition, the cannabinoid-like compound was identified to raise other “pro-survival” compounds in the brain, additional enhancing recovery. Collectively, by stopping the brain from harming itself and boosting the recovery method, this naturally occurring cannabinoid-like compound led to a substantially enhanced recovery.

Numerous persons are impacted by serious head injury each and every year. Rehabilitation is slow, and extra frequently than not individuals fail to make a complete recovery. This study suggests cannabinoids could be an productive option and possibly even permit extra persons make a complete recovery from their injury.

Cohen-Yeshurun, A. et al. (2011). N-arachidonoyl-serine is neuroprotective right after traumatic brain injury by decreasing apoptosis. Journal of Cerebral Blood Flow and Metabolism, 31(eight), 1768-1777.


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